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Context

Caribbean healthcare systems differ substantially in capacity, quality, and digital maturity across jurisdictions. OECD and World Bank reports (2020, 2023) highlight large variations in health expenditure, workforce availability, infrastructure, and health outcomes across the region. Small population sizes and fragmented governance structures further limit the ability of individual islands to independently provide comprehensive healthcare services. As a result, healthcare delivery in the Caribbean inherently depends on cross-border collaboration.

This interdependence is already visible in practice. Cervical and breast cancer screening programs connect Bonaire, St. Eustatius, and Saba with Curaçao and the Netherlands, while referral pathways also involve Aruba and Colombia. CARPHA member states similarly coordinate laboratory capacity and emergency response services. These initiatives demonstrate that regional cooperation is both necessary and feasible. However, most collaborations remain organized around isolated programs and bilateral agreements rather than a shared regional infrastructure. Consequently, existing initiatives scale poorly, duplicate integration efforts, and fail to support broader continuity of care across domains.

Strategic direction

To overcome the limitations of these fragmented and domain-specific initiatives, regional cooperation through interoperability has increasingly emerged as a strategic priority. This direction is reflected consistently across regional and international policy agendas, including CARICOM’s health framework (2016), PAHO’s strategic initiatives (2017, 2020, 2026), the joint PAHO/WHO-CARICOM cooperation strategy (2025), reports from the IDB’s Caribbean digital health initiatives (2024, 2026), and the WHO’s global strategy (2025). Collectively, these reports emphasize that cross-border exchange and use of health information are essential for improving continuity of care, regional surveillance, and health system resilience. Interoperability, defined as the ability of systems to exchange and meaningfully use information, therefore provides the foundational infrastructure required to transform isolated collaborations into a cohesive regional health ecosystem.

Current interoperability challenges

Despite this strategic alignment, operational implementation remains limited because the Caribbean lacks a dedicated interoperability framework. As described by Luna et al. (2019), interoperability initiatives require shared standards, governance agreements, and reusable architectural components. In their absence, healthcare organizations face inconsistent patient identification, manual and error-prone data transfers, and initiative-specific integrations that cannot easily be reused. Moreover, centralized approaches often encounter resistance due to concerns regarding national sovereignty and data ownership. Consequently, each new partnership frequently develops bespoke solutions instead of building upon common regional capabilities.

Reference architecture as intervention

A regional reference architecture could address these challenges by providing a shared yet flexible foundation for cooperation. Such an architecture would define common interoperability principles, governance structures, and reusable building blocks while remaining implementation- and technology-agnostic. By specifying semantic, syntactic, and technical standards, it would enable consistent and scalable data exchange across organizations and jurisdictions without requiring uniform local systems.

Why a Caribbean-specific architecture?

However, directly adopting generic international frameworks is unlikely to succeed in the Caribbean context. The region is characterized by heterogeneous policy landscapes (Bagolle et al. 2021), substantial variation in digital and technical maturity (PAHO 2021), linguistic and cultural diversity, and human resource capacity (OECD 2023). A Caribbean-specific reference architecture is therefore necessary to accommodate these heterogeneous conditions while still enabling regional interoperability. Such an approach allows islands to participate according to their local capabilities without imposing a rigid one-size-fits-all model that would be difficult to operationalize.